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(For faster updates on individual market-movers, Eikon users please use search string "STXBZ US"; for the Day Ahead newsletter, link.reuters.com/mex49s; for the Morning News Call newsletter, link.reuters.com/nex49s) U.S. stocks opened modestly higher on Wednesday, a day after the market ended flat with the S&P 500 snapping three straight days of declines. The Dow Jones industrial average was up 0.80 percent at 17,905.44, the S&P 500 was up 0.71 percent at 2,094.86 and the Nasdaq Composite was up 0.54 percent at 5,041.063.
** HCC INSURANCE HOLDINGS INC, $77.03, +35.88 pct
Tokio Marine Holdings Inc said on Wednesday it had agreed to buy U.S. specialty insurer HCC Insurance Holdings for $7.5 billion, in what would be the biggest M&A deal this year by a Japanese company.
** BOULDER BRANDS INC, $7, -21.17 pct
The natural packaged food maker said Chief Executive Stephen Hughes resigned and it expected sales to fall in the second quarter, sending its shares down 15.5 percent in premarket trading.
** GLOBEIMMUNE INC, $3.0545, -20.25 pct
The drug developer said it would cut most of its jobs and look for strategic alternatives, weeks after the mid-stage study of its lead pipeline drug failed to meet the main goal.
** FRANCESCA'S HOLDINGS CORP, $13.6, -15.42 pct
The women's apparel and accessories retailer reported lower-than-expected first-quarter sales, hurt by weak demand at its boutiques.
** SCORPIO BULKERS INC, $1.81, -16.59 pct
The dry bulk shipper said it would sell $200 million of its common stock in a public offering.
** BALLARD POWER SYSTEMS INC, $2.435, +7.27 pct
The Canadian fuel-cell products maker signed a deal with Chinese locomotives maker Tangshan Railway Vehicle Company to develop a new fuel cell module to power trams.
** CYPRESS SEMICONDUCTOR CORP, $13.175, +4.56 pct
** INTEGRATED SILICON SOLUTION INC, $20.39, -0.29 pct
Integrated Silicon Solution said it agreed to be acquired by Cypress Semiconductor on Wednesday, days after rejecting the fellow chipmaker's offer citing antitrust concerns.
** CTI BIOPHARMA CORP, $2.079, +5.53 pct
** BAXTER INTERNATIONAL INC, $64.57, +0.76 pct
The drug developer said a license was granted to Baxter on lead blood cancer drug pacritinib being tranferred to planned spinoff Baxalta. CTi BioPharma said it would receive about $32 million in two milestone payments earlier than expected.
** JOHNSON CONTROLS INC, $53.88, +4.50 pct
The auto parts maker said it was exploring strategic options for the separation of its automotive business.
** REGENERON PHARMACEUTICALS INC, $505.07, -4.00 pct
** SANOFI SA, $49.9, +0.95 pct
** ESPERION THERAPEUTICS INC, $77.28, -23.13 pct
A new type of cholesterol-lowering drug made by Sanofi and Regeneron Pharmaceuticals should be approved, an advisory committee to the U.S. Food and Drug Administration concluded on Tuesday. Most panelists said they would like to see use of the product limited, at least initially, to patients with a genetic predisposition to high cholesterol and those at high risk of cardiovascular disease who are on maximum doses of statin therapy.
Cholesterol drug developer Esperion's shares were also down.
** OXFORD INDUSTRIES INC, $86.58, +6.88 pct
The apparel retailer forecast current-quarter profit and sales above analysts' estimates and raised its full-year forecast, citing strong demand for its Lilly Pulitzer and Tommy Bahama clothing lines and store growth.
** SIGMA DESIGNS INC, $9.47, +5.93 pct
The company, which makes chips for Internet-based TV set-top boxes, on Tuesday reported first-quarter profit and revenue well above average analyst estimates.
** TRINITY INDUSTRIES INC, $29.815, +2.00 pct
A U.S. judge on Tuesday ordered the company to pay $663.4 million after a federal jury found it liable for failing to tell a government highway agency about changes made to a widely used guardrail system that raised safety concerns.
** NEW RESIDENTIAL INVESTMENT CORP, $15.95, -4.09 pct
The investment management company announced an offering 31.5 million shares, representing about 16 percent of outstanding shares as of April 30.
** NETFLIX INC, $668.67, +3.33 pct
The company's shareholders on Tuesday approved a massive increase in the number of shares the company is authorized to issue, the first step toward a possible stock split.
** QUIKSILVER INC, $0.8063, -4.96 pct
D.A. Davidson cuts rating on the stock to "neutral" from "buy" a day after the company reported a bigger-than-expected second-quarter loss and withdrew its full-year forecast.
** IGNYTA INC, $17.63, -2.49 pct
The company said on Tuesday that it would offer about $75 million of its common stock to fund research and development activities.
** TARGET CORP, $79.48, +0.74 pct
The company said it would double its share buyback program to $10 billion and boost its quarterly dividend by 7.7 percent, confirming the contents of a statement it published inadvertently and took off its website earlier on Tuesday. (Compiled By Manya Venkatesh in Bengaluru; Edited by Don Sebastian)