(For more market insights, including options activity, click on ; for the Day Ahead newsletter link.reuters.com/mex49s; for the Morning News Call newsletter, link.reuters.com/nex49s) U.S. stock index futures were mostly flat on Wednesday. Dow Jones industrial average futures were unchanged at 0, S&P 500 futures were up 0.11 percent at 1,879.9 and Nasdaq 100 futures were up 0.29 percent at 3,660.75.
** MANNKIND CORP, Tuesday close $4.02, +95.27 pct premarket
U.S. health advisers on Tuesday recommended approval of the company's inhaled diabetes drug, and said the experimental treatment could help some patients, especially those wary of needles typically used with traditional insulin therapy.
** APOLLO EDUCATION GROUP, Tuesday close $35.16, -3.30 pct premarket
The company reported lower-than-expected quarterly revenue as enrollments declined 16.8 percent at its flagship University of Phoenix.
The company also said it had received a subpoena from the U.S. Department of Education's Office of Inspector General, seeking information about the operations of the Northeast region of the University of Phoenix.
** AMERICA MOVIL, Tuesday close $20.33, -2.21 percent after market
Carlos Slim's phone and Internet giant has challenged a ruling by Mexico's new telecommunications regulator that says the company dominates its market.
** BLACKBERRY LTD, Tuesday close $8.1, -0.62 pct premarket
** T-Mobile U.S. Inc, Tuesday close $33.48
BlackBerry said on Tuesday it will not renew its license with T-Mobile to sell BlackBerry products after the current contract expires on April 25.
** GlaxoSmithKline Plc, Tuesday close $53.3, -0.68 pct premarket
** AGENUS INC, Tuesday close $3.31, -9.37 pct premarket
GlaxoSmithKline has stopped a high-profile clinical trial using a novel vaccine to fight lung cancer after deciding it will not be possible to find a sub-group of patients who might benefit.
Agenus contributed technology to the treatment, the MAGE-A3 vaccine, which is aimed at people with established disease, helping their immune systems to prevent the recurrence of disease post surgery.
** APPLE INC, Tuesday close $541.65, +0.28 pct premarket
Renesas Electronics Corp is talking with Apple and other potential buyers of a stake in a smartphone display chip unit, as the struggling Japanese chipmaker restructures its business around the automotive industry, said a person familiar with the matter.
** MONSANTO CO, Tuesday close $113.99
The world's largest seed company is likely to report second-quarter results before the opening bell. The company re-ported higher-than-expected quarterly earnings in the first quarter as a rise in herbicide sales offset a decline in its corn business.