(For faster updates on individual market-movers, Eikon users please use search string "STXBZ US"; for the Day Ahead newsletter, link.reuters.com/mex49s; for the Morning News Call newsletter, link.reuters.com/nex49s) U.S. stocks fell sharply in early afternoon trading on Wednesday, led by health insurers after Humana reported an unexpected pick-up in hospital admissions in March and April. The Dow Jones industrial average was down 0.22 percent at 18,070.23, the S&P 500 was down 0.29 percent at 2,108.67 and the Nasdaq Composite was down 0.48 percent at 5,030.966.
** LUMBER LIQUIDATORS HOLDINGS INC, $27.79, -16.85 pct
The hardwood flooring retailer reported a 2 percent fall in net sales so far in April and said it could not provide a full-year forecast.
** TWITTER INC, $39.52, -6.51 pct
The Microblogging site reported quarterly revenue that fell short of Wall Street estimates and cut its full-year forecast due to weak demand for its new direct response advertising.
** ALIBABA GROUP HOLDING LTD, $82.14, -3.46 pct
The Chinese e-commerce company is freezing hiring for the rest of the year because it has grown "too quickly", Executive Chairman Jack Ma told staff.
** BLUEBIRD BIO INC, $134.25, +1.11 pct
Piper Jaffray raised its price target on the drug developer's shares, saying the company's gene therapy, LentiGlobin, will emerge as a curative therapy for most sickle cell anemia patients this year.
** SPX CORP, $79.75, -6.48 pct
The maker of pumps, valves and filtration equipment posted first-quarter revenue that missed estimates due to a stronger dollar.
** INPHI CORP, $20.33, +10.37 pct
The chipmaker posted a first-quarter profit marginally above estimates and forecast second-quarter revenue and profit in line with estimates.
RBC Capital Markets raised its price target on the stock to $25 from $24.
** WYNN RESORTS LTD, $109.996, -15.70 pct
At least eight brokerages cut target prices on the casino operator's stock by between $10 and $40 after the company reported a weaker-than-expected first-quarter profit, hurt by lower revenue from Macau.
** MYLAN NV, $74.38, +2.30 pct
** PERRIGO CO PLC, $186.7, +0.17 pct
Mylan boosted its cash-and-stock offer to buy Perrigo to $34.10 billion, a bid which is expected to be rejected, a person familiar with the matter told Reuters.
** HUMANA INC, $167.385, -7.58 pct
The health insurer reported a lower-than-expected first-quarter profit, due to rise in claims in its retail and group segments.
** OPENTEXT CORP, $51.76, -6.55 pct
At least five brokerages cut price targets on the stock after the Canadian business-software maker reported lower-than-expected third-quarter profit and revenue.
** HERCULES OFFSHORE INC, $0.78, +12.21 pct
The drilling contractor reported a smaller-than-expected quarterly loss, helped by lower costs.
** B&G FOODS INC, $30.94, -2.83 pct
The food distributor said its offering of 4.2 million shares of common stock was priced at $30.60 per share.
** BUFFALO WILD WINGS INC, $158.75, -13.58 pct
The restaurant operator reported first-quarter results that missed estimates as chicken wings prices soared 41 percent versus last year's unusually low price.
** KBR INC, $17.03, +7.31 pct
The engineering and construction company posted a first-quarter profit versus a year-ago loss, helped by cost cuts.
** LOGMEIN INC, $66.08, +12.73 pct
The remote-access software maker reported a better-than-expected first-quarter profit.
** INTERNAP CORP, $9.36, -10.26 pct
D. A. Davidson cut its price target on the network services provider to $11, while Cowen cut it to $11 from $12.
** BEL FUSE INC, $19.99, +10.56 pct
The circuit protection equipment maker's first-quarter sales jumped 71.8 percent, helped by higher sales from its power solutions and connectivity solutions business.
** NOVADAQ TECHNOLOGIES INC, $10.915, -12.47 pct
The Canadian medical imaging product maker posted a bigger-than-expected first-quarter loss of $20 per share on Tuesday as revenue fell and costs rose.
** BARRETT BUSINESS SERVICES INC, $45.28, +11.09 pct
The management consulting company's first-quarter revenue rose 24 percent, helped by higher revenue in its professional employer services business.
** AMEDISYS INC, $27.56, +5.07 pct
The home health and hospice company reported a better-than-expected first-quarter profit, helped by higher demand for its healthcare services.
** MICROSTRATEGY INC, $184.31, +8.61 pct
The business software provider's first-quarter profit beat the average analyst estimate as operating expenses fell 35 percent to $74.1 million.
** M/A-COM TECHNOLOGY SOLUTIONS HOLDINGS INC, $32.89, +2.17 pct
The chipmaker reported higher-than-expected second-quarter revenue and profit, helped by strength in its automotive business.
** AVERY DENNISON CORP, $54.85, +5.81 pct
The maker of tickets, tags and labels reported higher-than-expected first-quarter profit and revenue, helped by higher sales in its pressure-sensitive materials business, and raised its 2015 profit forecast.
** HELEN OF TROY LTD, $88.55, +10.90 pct
The personal care products and kitchenware maker reported higher-than-expected fourth-quarter adjusted profit and revenue, driven by strong cold and flu season and demand for new healthcare products.
** STRATASYS, $41.06, -19.96 pct
** 3D SYSTEMS, $25.17, -3.78 pct
** VOXELJET, $8.37, -5.10 pct
Stratasys estimated first-quarter profit below analysts' expectations, citing a stronger dollar and a decline in spending by clients, particularly in North America.
Shares of other 3D printer makers also fell.
** DIXIE GROUP INC, $10.19, -1.64 pct
The carpet and rugs maker reported a first-quarter net loss versus a profit a year earlier.
** CARTER'S INC, $98.74, +6.21 pct
The children's apparel marketer reported better-than-expected first-quarter adjusted profit and revenue, driven by Carter's and OshKosh divisions in the United States.
** EPIZYME INC, $18.155, -5.49 pct
The drug developer's first-quarter loss was bigger than expected, hurt by a jump in R&D expenses and a fall in collaboration revenue.
** VERISK ANALYTICS INC, $76.25, +4.97 pct
The data analytics firm reported better-than-expected first-quarter profit and revenue as sales in its decision analytics business, which helps customers make decisions about managing assets and associated risks, rose about 17 percent.
** HILTON WORLDWIDE HOLDINGS INC, $29.975, +1.82 pct
The hotel operator reported higher-than-expected quarterly revenue, helped by higher room rates and increased occupancy.
** GRUBHUB INC, $41.02, -9.45 pct
The online food order and delivery company's quarterly profit missed market estimates due to a jump in expenses and taxes.
** MASTERCARD INC, $90.51, +0.31 pct
The world's No. 2 debit and credit card company reported a 17 percent rise in quarterly profit as more people used its cards worldwide.
** GOODYEAR TIRE & RUBBER CO, $28.66, +5.56 pct
The largest U.S. tire maker reported a better-than-expected quarterly profit as it shrugged off the effect of a stronger dollar by managing its costs.
** GENERAL DYNAMICS CORP, $137.2, +2.79 pct
The U.S. weapons maker on Wednesday reported higher-than-expected earnings and revenue for the first quarter.
** STARWOOD HOTELS & RESORTS WORLDWIDE INC, $87.35, +8.11 pct
The company, which owns the St. Regis and Sheraton hotel brands, said it was exploring strategic and financial alternatives and "no option is off the table."
** GARMIN LTD, $45.64, -3.90 pct
The maker of GPS-based gadgets' quarterly revenue rose much less than expected as a strong dollar ate into its overseas income.
** HANNON ARMSTRONG SUSTAINABLE INFRASTRUCTURE CAPITAL , $19, -1.71 pct
The company, a provider of debt and equity financing for infrastructure projects, said it will issue 4 million shares, representing 14 percent of its outstanding stock, in a public offering.
** ONCOLYTICS BIOTECH INC, $0.73, +3.38 pct
The drug developer's lead pancreatic cancer drug, Reolysin, got orphan drug status from the European health regulator.
** SPIRIT AIRLINES INC, $69.36, -10.94 pct
** UNITED CONTINENTAL HOLDINGS, $59.54, -3.06 pct
** AMERICAN AIRLINES, $49.08, -4.12 pct
** DELTA AIRLINES, $45.17, -2.23 pct
** SOUTHWEST AIRLINES CO, $40.9, -2.36 pct
** ALASKA AIR GROUP, $65.24, -1.85 pct
** JETBLUE AIRWAYS CORP, $20.75, -1.28 pct
Spirit's poor results, weak U.S. economic data and rising oil prices combine to clip the airline sector's wings.
** ARIAD PHARMACEUTICALS INC, $9.2699, +4.51 pct
Sarissa Capital Management LP said Ariad's Harvey Berger would retire as CEO as part of a deal to settle the hedge fund's proxy battle with the drugmaker.
** XPO LOGISTICS INC, $48.93, +15.27 pct
The company has agreed to buy France's Norbert Dentressangle SA for $3.53 billion, including debt, in a deal it says will make it one of the top 10 logistics company in the world.
** GENWORTH FINANCIAL INC, $8.98, +12.39 pct
The life and mortgage insurer is considering strategic options, including going private or selling its global life and annuity insurance unit (GLAIC), Chief Executive Tom McInerney said.
** AKAMAI TECHNOLOGIES INC, $74.56, -1.99 pct
The company, whose service helps speed up delivery of online content, forecast current-quarter profit below analysts' expectations, citing a stronger dollar.
** UNITED STATES STEEL CORP, $24.03, -10.27 pct
The U.S. steelmaker cut its full-year forecast for adjusted earnings before interest, taxes, depreciation and amortization forecast to $700 million to $900 million from $1.1 billion to $1.4 billion.
** TEMPUR SEALY INTERNATIONAL INC, $61.57, +2.11 pct
The mattress maker reported a 5.4 percent rise in quarterly sales, helped by higher demand in its North America business, the company's largest market. (Compiled by Avik Das in Bengaluru; Editing by Simon Jennings)