March 20, 2009 / 1:06 AM / 8 years ago

Maggots no wonder cure for festering wounds

<p>A researcher displays a box containing maggots of the lucilia cuprina species of fly at the Maggot Research Laboratory at Nanyang Technologcal University in Singapore October 23, 2007.Vivek Prakash</p>

LONDON (Reuters) - Putting flesh-eating maggots into open wounds may not be such a great idea after all.

They do clean wounds more quickly than normal treatment but this does not lead to faster healing, results of the world's first controlled clinical trial of maggot medicine showed on Friday.

Some patients also found so-called larval therapy more painful, according to the study in the British Medical Journal.

Gruesome as it sounds, maggots have a long history in medicine. Napoleon's battle surgeon was a maggot enthusiast, and they were put to work during the American Civil War and in the trenches in World War One.

More recently, medical experts have been looking again at the creatures' healing powers, including their potential to prevent dangerous infections like methicillin-resistant Staphylococcus aureus (MRSA).

To find out more, researchers at Britain's University of York recruited 267 patients with venous leg ulcers and treated them either with maggots or hydrogel, a standard wound-cleaning product.

They found no significant difference in outcomes or cost.

"It doesn't seem to be worth pursuing in this particular group of patients, if what you are aiming for is quicker healing," researcher Nicky Cullum said in a telephone interview.

Maggots may yet have advantages in some specialized areas, such as preparing patients for skin grafts, where faster wound cleaning means patients can be moved into surgery more swiftly. But establishing this will require further clinical studies.

Larval therapy works because maggots eat only dead and rotting tissue, leaving a clean wound. They do not burrow into healthy flesh, preferring to eat each other when they run out of food.

Editing by Charles Dick

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