Sex virus blamed for rise in head and neck cancers

Thu Mar 25, 2010 8:09pm EDT
 
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By Kate Kelland

LONDON (Reuters) - The number of serious head and neck cancers linked to a virus spread by oral sex is rising rapidly and suggests boys as well as girls should be offered protection through vaccination, doctors said on Friday.

Despite an overall slight decline in most head and neck cancers in recent years, cases of a particular form called oropharyngeal squamous cell carcinoma (OSCC) have increased sharply, particularly in the developed world.

This growth seems to be linked to cancers caused by the human papillomavirus (HPV), the scientists said in a report in the British Medical Journal.

Two vaccines -- Cervarix, made by GlaxoSmithKline, and Gardasil, made by Merck & Co -- can prevent HPV, which causes virtually all cases of cervical cancer, the second most common cancer in women worldwide.

Many rich nations have launched HPV immunization programs for girls to try to protect them from the common sexually transmitted virus before they become sexually active.

The scientists, led by Hisham Mehanna of the Institute of Head and Neck Studies at Britain's University Hospital Coventry, said that while including boys in immunization plans was previously seen as too expensive, it may be time to look again.

"We need to look at the evidence again to re-evaluate the cost-effectiveness of male children in light of this new and rapidly rising incidence," he said in a telephone interview.

More than 500,000 cases of cervical cancer are diagnosed annually in women and it kills around 200,000 a year. Head and neck cancer is the sixth most common cancer among men and women, with about 640,000 new cases each year worldwide.   Continued...