(For faster updates on individual market-movers, Eikon users please use search string "STXBZ US"; for the Day Ahead newsletter, link.reuters.com/mex49s; for the Morning News Call newsletter, link.reuters.com/nex49s) Wall Street was set to open little changed on Wednesday with investors cautious ahead of the release of minutes from last month's Federal Reserve meeting, which is expected to shed light on when interest rates will be hiked. Dow Jones industrial average futures were up 0.14 percent at 18,309, S&P 500 futures were up 0.07 percent at 2,126 and Nasdaq 100 futures were up 0.16 percent at 4,508.5.
** LPATH INC, Tuesday close $1.71, -75.60 pct premarket
The company said it would reduce its workforce and cut costs as its experimental drug failed a mid-stage study in patients with wet age-related macular degeneration, a leading cause of blindness in the elderly.
** SAREPTA THERAPEUTICS INC, Tuesday close $16.38, +46.21 pct premarket
The drugmaker says to begin "rolling submission" of marketing application for experimental muscle disorder drug eteplirsen.
** AMERICAN EAGLE OUTFITTERS INC, Tuesday close $15.74, +8.01 pct premarket
The teen apparel retailer reported an 8.3 percent rise in quarterly sales, helped by strong demand for its clothes and fewer discounts.
** AVEO ONCOLOGY, Tuesday close $1.34, +15.67 pct premarket
The drug developer said it had received positive response from the U.S FDA regarding approval of its kidney cancer drug, tivozanib.
** LENDINGCLUB CORP, Tuesday close $17.62, +3.86 pct premarket
Morgan Stanley upgrades the stock to "overweight". "We believe the stock is overly discounting risk from increased competition, while under appreciating the significant secular growth potential," Morgan Stanley analysts write in a note.
** YINGLI GREEN ENERGY HOLDING CO LTD, Tuesday close $0.94, +19.15 pct premarket
The Chinese solar company says it is "optimistic about and confident in its ability to continue servicing the global solar market" and it has taken "positive and substantive actions" related to its debt repayment plans. Yingli's shares fell in past two sessions after company said late on Friday that there was "substantial doubt" over its ability to continue as going concern due to its debt.
** ACHILLION PHARMACEUTICALS INC, Tuesday close $10.68, -10.21 pct premarket
** JOHNSON & JOHNSON, Tuesday close $103.96, +0.62 pct premarket
Achillion said it will collaborate with Johnson & Johnson to develop and market its hepatitis C drugs including an oral regimen that could work on all genotypes and shorten treatment time.
** LOWE'S COS INC, Tuesday close $71.83, -5.26 pct premarket
The No.2 U.S. home improvement chain by sales reported a 7.9 percent rise in quarterly profit as an improving job market encouraged Americans to spend on renovations.
** ETSY INC, Tuesday close $21, -19.19 pct premarket
The online marketplace for handmade goods says Q1 net loss widened as operating expenses rise about 73 percent. The company says if foreign exchange rates continue at current levels, it will likely continue to impact buyer behavior outside of the U.S.
** CIMAREX ENERGY CO, Tuesday close $114.76, -3.27 pct premarket
The oil and gas producer announces a public offering of 6 million shares, representing nearly 7 percent of its outstanding shares as of March 30. The offering is expected to be priced at $108-$111 per share, a discount of 3.3-5.9 pct to the stock's Tuesday close, sources tell Reuters.
** UBS GROUP AG, Tuesday close $21.13, +3.31 pct premarket
UBS will plead guilty to rigging benchmark interest rates and pay $545 million to U.S. authorities to settle their probe into alleged manipulation of foreign exchange rates.
** HORMEL FOODS CORP, Tuesday close $55.79, -0.02 pct premarket
The maker of Spam lunch meat reported lower-than-expected quarterly sales and said its Jennie-O Turkey Store business would be "significantly challenged" due to an outbreak of avian flu in the United States.
** UNITED TECHNOLOGIES CORP, Tuesday close $119.07, +0.53 pct premarket
United Technologies is in talks with potential buyers for its Sikorsky Aircraft business, according to four people familiar with the situation.
** GENERAL ELECTRIC CO, Tuesday close $27.35, +0.00 pct premarket
General Electric would lose a $350-million deal to build locomotives for Angola, and perhaps billions of dollars more in future export opportunities, if Congress closes the U.S. Export-Import Bank, a senior GE executive told Reuters.
** FIAT CHRYSLER AUTOMOBILES NV, Tuesday close $15.6, +0.06 pct premarket
U.S. vehicle safety regulators' tougher posture toward automakers is a "new phase" in the government's relations with the industry and will likely mean higher costs, Fiat Chrysler Automobiles Chief Executive Sergio Marchionne said Tuesday.
** CABLEVISION SYSTEMS CORP, Tuesday close $21.07, +1.57 pct premarket
** VERIZON COMMUNICATIONS INC, Tuesday close $49.55, +0.20 pct premarket
Cablevision sued Verizon on Tuesday, seeking a judge's finding that its television commercial claiming Verizon's FiOS service does not solely use fiber optic cable is truthful.
** COMPUTER SCIENCES CORP, Tuesday close $67.66, +3.71 pct premarket
The technology consulting service provider said it would split into two public companies - one to serve commercial and government clients globally and one to serve public sector clients in the United States.
** J.C. PENNEY CO INC, Tuesday close $8.55, -0.12 pct premarket
A federal judge certified a class-action lawsuit that accuses J.C. Penney of marking up retail prices on apparel and accessories to trick shoppers into believing they were getting big discounts when the items were advertised on sale.
** VODAFONE GROUP PLC, Tuesday close $36.2, +1.96 pct premarket
** LIBERTY GLOBAL PLC, Tuesday close $53.11
Vodafone's shares rose after the chairman of Liberty, John Malone, said the two companies would make a "great fit", reigniting long-running merger speculation.
** SALESFORCE.COM INC, Tuesday close $71.48, +0.43 pct premarket
German software company SAP's chief executive once again ruled out any move to acquire Salesforce.com, then went further by saying that its richly valued rival is unlikely to be acquired by any other player in the industry.
** AUTODESK INC, Tuesday close $57.52, -1.34 pct premarket
The company, which makes computer-aided design software, forecast lower-than-expected profit and revenue for the second quarter, citing a stronger dollar.
** AMGEN INC, Tuesday close $163.56, +0.26 pct premarket
Amgen's new cholesterol drug Repatha could be recommended for approval in Europe as early as this week, putting it ahead in a race with a rival product from Sanofi .
** VALEANT PHARMACEUTICALS INTERNATIONAL INC, Tuesday close $227.65
Valeant's exposure to Asia's growing middle class could help lead to the quintupling of sales in that market to around $5 billion by 2020, Chief Executive Michael Pearson said on Tuesday.
Valeant is in talks to buy Egyptian drugmaker Amoun Pharmaceutical Co to expand its veterinary and human medicines portfolio, Bloomberg reported, citing people familiar with the matter.
** MEDTRONIC PLC, Tuesday close $78.44
Medtronic said on Tuesday fourth-quarter revenue would be higher than expected, boosted by strong U.S. sales of its heart devices, and projected earnings would be at the upper end of its previously forecast range.
** MCDONALD'S CORP, Tuesday close $100.68, +0.08 pct premarket
Thousands of McDonald's workers seeking a minimum wage of $15 per hour and the right to unionize are expected to swarm the fast-food giant's headquarters for two days of protests that will coincide with the fast-food chain's annual meeting on Thursday.
** WHIRLPOOL CORP, Tuesday close $190.03
Whirlpool and Anheuser-Busch on Tuesday started selling a countertop appliance that makes soda, juice and coffee with single-serve capsules, marking the start of a joint venture worth more than $70 million.
** CAL-MAINE FOODS, Tuesday close $58.3
Shares of the producer of fresh eggs could continue to benefit from diminished supplies caused by the recent avian flu outbreak and from near-term buying by short-sellers.
** AUTOLIV INC, Tuesday close $127.1, +3.19 pct premarket
The Swedish auto safety gear maker said on Wednesday it was ready to boost production capacity to meet increased demand as Japanese competitor Takata Corp recalls an additional 17 million airbag inflators.
** TOTAL SA, Tuesday close $52.32, +0.55 pct premarket
The French oil major Total has started gas and condensate production at its Termokarstovoye field in northern Siberia, the first of a string of projects with Russia's Novatek to come to fruition, it said on Wednesday.
** DYCOM INDUSTRIES INC, Tuesday close $46.07, +16.67 pct premarket
The specialty contracting services provider forecasts Q4 profit and revenue above analysts' estimates. The company expects Q4 profit of 74-82 cents and revenue of $550 million-570 million while analysts expect a profit of 58 cents on revenue of 522.8 million, according to Thomson Reuters I/B/E/S. (Compiled by Kshitiz Goliya in Bengaluru; Edited by Maju Samuel)