(For faster updates on individual market-movers, Eikon users please use search string "STXBZ US"; for the Day Ahead newsletter, link.reuters.com/mex49s; for the Morning News Call newsletter, link.reuters.com/nex49s) Wall Street opened lower on Wednesday after a setback in Greece's debt talks even as data showed that the U.S. economy's first-quarter contraction was smaller than earlier thought. Dow Jones industrial average futures were down 0.37 percent at 18,000, S&P 500 futures were down 0.15 percent at 2,113.25 and Nasdaq 100 futures were down 0.06 percent at 5,156.91.
** TRANSITION THERAPEUTICS INC, $2.61, -71.29 pct
The drug developer said a mid-stage study of its experimental neuropshychiatric drug, ELND005, did not meet the main goal of significant reduction in agitation and aggression.
** STAPLES INC, $16.02, -2.91 pct
** OFFICE DEPOT INC, $8.9, -2.31 pct
Staples' $6.3-billion acquisition of Office Depot less likely after a Federal judge blocked food service distributor Sysco Corp's deal to buy US Foods Inc, NY Post reported.
** BOX INC, $18.99, +8.21 pct
The cloud storage company said it will boost its cloud platform with world's largest technology services provider IBM Corp's security and analytics offerings. Box enterprise customers will be able to store content on IBM's cloud.
** CELATOR PHARMACEUTICALS INC, $3.12, +39.29 pct
The drug developer said its experimental chemotherapy combination, CPX-351, showed relative improvement in response rate in patients with a form of blood cancer in a late-stage study.
** CATALYST PHARMACEUTICALS INC, $4.3, +39.29 pct
The drugmaker said its experimental drug, vigabatrin, reduced involuntary movements and vocalizations called tics in patients with Tourette's in an early study.
** MEETME INC, $1.699, +17.99 pct
The social game and app maker raised second-quarter revenue and adjusted EBITDA forecast on progress in transitioning management of advertising inventory in-house earlier this month.
** ALCOBRA LTD, $7.0201, -16.33 pct
The Israel-based drug developer said its drug failed in a mid-stage trial to treat a type of genetic disorder that could cause autism and attention deficit hyperactivity disorder..
** LOCAL CORP, $0.0698, -75.01 pct
The advertising services provider filed for Chapter 11 bankruptcy protection.
** LENNAR CORP, $51.18, +4.45 pct
The No.2 U.S. homebuilder by sales reported a 33 percent rise in quarterly profit as it sold more homes at higher prices and said orders rose 17.6 percent.
** DELHAIZE GROUP SA, $23.01, -6.27 pct
Dutch-based supermarkets operator Ahold has reached a deal to buy Belgian peer Delhaize, the companies announced on Wednesday, in a move that will create the sixth-largest food retailer in the United States and the biggest in Europe's Benelux region.
** NETFLIX INC, $692.29, +1.63 pct
The online video streaming service said on Tuesday its board of directors approved a seven-for-one stock split.
The split will be effected in the form of a stock dividend of six additional shares for each outstanding share, the company said in a statement.
** VANDA PHARMACEUTICALS INC, $13.5, +4.61 pct
The drugmaker said on Tuesday that Fanapt prevented relapse in adult schizophrenic patients in a study. The study showed that 76 percent patients given the drug remained relapse-free, compared with 36 percent on placebo.
** GREAT BASIN SCIENTIFIC INC, +6.83 pct
The diagnostics company said it got a research grant from National Institutes of Health to develop a fast blood test for the Enterobacteriaceae superbug, which infects the urinary tract, blood, and wounds.
Compiled by Anya George Tharakan; Editing by Sriraj Kalluvila